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  • Shining light on night blindness

    Shining light on night blindness

    A dangerously blurry view of cars, streetlights, headlights through a car window at night; concept is night blindness

    Animals renowned for their outstanding night vision include owls, cats, tarsiers (a tiny primate in Southeast Asia) — and even the dung beetle.

    But humans? Not so much.

    Over time, many people suffer from night blindness, also known as nyctalopia. This condition makes seeing in dim or dark settings difficult because your eyes cannot adjust to changes in brightness or detect light.

    What are the dangers for those experiencing night blindness?

    Night blindness is especially problematic and dangerous when driving. Your eyes cannot adjust between darkness and the headlights of oncoming vehicles, other cars may appear out of focus, and your depth perception becomes impaired, which makes it difficult to judge distances.

    Night blindness also may affect your sight at home by making it hard for your vision to quickly adjust to a dark room after turning off the lights. “This can cause people to bump into furniture or trip and suffer an injury,” says Dr. Isabel Deakins, an optometrist with Harvard-affiliated Massachusetts Eye and Ear.

    What happens in the eye to create night blindness?

    The ability to see in low-light conditions involves two structures in the eye: the retina and the iris.

    The retina, located in the back of the eye, contains two types of light-detecting cells called cones and rods. The cones handle color vision and fine details while the rods manage vision in dim light.

    The iris is the colored part of your eye. It contains muscles that widen or narrow the opening of your pupil to adjust how much light can enter your eyes.

    If your irises don’t properly react, the pupils can dilate and let in too much light, which causes light sensitivity and makes it hard to see in bright light. Or your pupils may remain too small and not allow in enough light, making it tough to see in low light.

    What causes night blindness?

    Night blindness is not a disease but a symptom of other conditions. “It’s like having a bruise on your body. Something else causes it,” says Dr. Deakins.

    Several conditions can cause night blindness. For instance, medications, such as antidepressants, antihistamines, and antipsychotics, can affect pupil size and how much light enters the eye.

    Eye conditions that can cause night blindness include:

    • glaucoma, a disease that damages the eye’s optic nerves and blood vessels
    • cataracts, cloudy areas in the lens that distort or block the passage of light through the lens
    • dry eye syndrome.

    However, one issue that raises the risk of night blindness that you can’t control is age. “Our eyes react more slowly to light changes as we age, and vision naturally declines over time,” says Dr. Deakins.  “The number of rods in our eyes diminish, pupils get smaller, and the muscles of the irises weaken.”

    What helps if you have night blindness?

    If you notice any signs of night blindness, avoid driving and get checked by an eye care specialist like an optometrist or ophthalmologist. An eye exam can determine if your eyeglass prescription needs to be updated.

    “Often, a prescription change is enough to reduce glare when driving at night," says Dr. Deakins. “You may even need separate glasses with a stronger eye prescription that you wear only when driving at night.”

    Adding an anti-reflective coating to your lens may help to cut down on the glare of the headlights of an oncoming car. However, skip the over-the-counter polarized driving glasses sold at many drug stores. "These may help cut down on glare, but they don't address the causes of night blindness," says Dr. Deakins.

    An eye exam also will identify glaucoma or cataracts, which can be treated. Glaucoma treatments include eyedrops, laser treatment, or surgery. Cataracts are corrected with surgery to replace the clouded lens with an artificial one. Your eye care specialist can also help identify dry eye and recommend treatment.

    Ask your primary care clinician or a pharmacist if any medications that you take may cause night blindness. If so, it may be possible to adjust the dose or switch to another drug.

    Three more ways to make night driving safer

    You also can take steps to make night driving safer. For example:

    • Wash the lenses of your glasses regularly. And take them to an optician to buff out minor scratches.
    • Keep both sides of your front and rear car windshields clean so that you can see as clearly as possible.
    • Dim your dashboard lights, which cause glare, and use the night setting on your rearview mirror.

    About the Author

    photo of Matthew Solan

    Matthew Solan, Executive Editor, Harvard Men's Health Watch

    Matthew Solan is the executive editor of Harvard Men’s Health Watch. He previously served as executive editor for UCLA Health’s Healthy Years and as a contributor to Duke Medicine’s Health News and Weill Cornell Medical College’s … See Full Bio View all posts by Matthew Solan

    About the Reviewer

    photo of Howard E. LeWine, MD

    Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

    Dr. Howard LeWine is a practicing internist at Brigham and Women’s Hospital in Boston, Chief Medical Editor at Harvard Health Publishing, and editor in chief of Harvard Men’s Health Watch. See Full Bio View all posts by Howard E. LeWine, MD

  • Is the portfolio diet the best diet ever?

    Is the portfolio diet the best diet ever?

    White table with healthy plant-based foods including Buddha bowl, lettuce wraps, colorful vegetables, grains, legumes, and dips

    News flash: What we eat can play a pivotal role in warding off — or treating — disease and enhancing quality of life. You may already believe this, and certainly mounting evidence supports that idea. But on the cluttered shelf of diets claiming top health benefits, which one ranks as the absolute best?

    That’s a trick question. In fact, there is no single best diet. A good diet for me may be different from what’s best for you. And for either of us, there may be several good choices with no clear winner.

    How can you choose the right diet for you?

    When thinking about what diet might be best for you, ask yourself:

    • What goals are most important? A goal might be weight loss, improved health, avoiding disease, or something else.
    • How do you define “best”? For some people, best means the diet with the highest number of health benefits. For others, it may focus on one specific health benefit, such as lowering cholesterol. Still other people may prefer a diet that delivers the greatest benefit for the lowest cost. Or a diet that is healthy and also easy to stick with.
    • What health problems do you have? One diet may have an advantage over another depending on whether you have cancer, cardiovascular disease, diabetes, or none of these.
    • Which foods do you like best? Your tastes, culture, and location may shape your dietary preferences, and powerfully affect how likely you are to stick with a specific diet.

    Which diets are high in health benefits?

    Two very well studied diets demonstrate clear benefit, including lowering risk for heart disease and stroke and reducing high blood pressure: the Mediterranean diet and the DASH diet.

    But the portfolio diet may be as good as or better than these plans, at least for combatting cardiovascular disease that contributes to clogged blood vessels, heart attacks, and stroke. What? You’ve never heard of the portfolio diet? You’re not alone.

    What is the portfolio diet?

    Just as a financial advisor may recommend having a diverse investment portfolio — not just stocks, not just bonds — the portfolio diet follows suit. This largely plant-based diet focuses on diverse foods and food groups proven to lower harmful blood lipids, including LDL (so-called bad cholesterol) and triglycerides.

    If you choose to follow this eating pattern, you simply need to learn which foods have a healthy effect on blood lipids and choose them in place of other foods. For some people, this only requires small tweaks to embrace certain foods while downplaying other choices. Or it may call for a bigger upheaval of longtime eating patterns.

    Which foods are encouraged in the portfolio diet?

    Below are the basics. Eating more of these foods regularly may help lower levels of harmful blood lipids:

    • plant-based proteins such as soy, beans, tofu, peas, nuts, and seeds
    • high-fiber foods such as oats, barley, berries, apples, and citrus fruit; other examples include bran, berries, okra, and eggplant
    • phytosterols, which are a natural compound in plant-based foods such as whole grains, fruits, vegetables, and nuts (other sources are foods fortified with phytosterols or dietary supplements)
    • plant-based oils high in monounsaturated fat such as olive oil, avocado oil, safflower oil, and peanut oil.

    See? Some of your favorite foods make the cut. That’s a major strength of this approach: the list of recommended foods is long. So, it’s likely that you’re already eating and enjoying some of the recommended foods.

    Which foods are not part of the portfolio diet?

    It’s worth highlighting foods that are not on this list, such as

    • red meat
    • highly processed foods
    • refined grains and added sugar, which may contribute to chronic inflammation
    • butter, cream, and other dairy products high in saturated fat and cholesterol.

    What can the portfolio diet do for you?

    Researchers have shown that the portfolio diet can improve blood lipids. But can it also lower the risk of heart attack, stroke, and other cardiovascular problems?

    Yes, according to a 2023 study published in Circulation. More than nearly 17,000 people kept careful food diaries for 30 years. Those who most closely followed the portfolio diet, compared with those who followed it the least, were more likely to have favorable lipids and inflammation. They were also 14% less likely to have a heart attack, and 14% less likely to have a stroke.

    This was true even after accounting for factors that could affect cardiovascular disease risk, such as taking cholesterol-lowering medications, exercise, smoking, or having diabetes or a family history of cardiovascular disease.

    Because this was an observational study, it can’t conclusively prove that the portfolio diet, rather than another factor, was responsible for the observed cardiovascular benefits. And we don’t know how much benefit came from reducing or eliminating certain types of foods, rather than from the specific foods eaten.

    Does the portfolio diet help people lose weight or deliver other health advantages?

    What about the portfolio diet for weight loss? Although some people lose weight on the portfolio diet, it’s not billed as a weight-loss diet. Understanding its potential benefit for other conditions such as obesity, cognitive decline, diabetes, and cancer awaits further research.

    Go beyond diet to boost health

    Of course, diet is not the only way to improve cardiovascular health and your overall health. You’ll stay healthier by

    • not smoking
    • getting regular exercise
    • maintaining a healthy blood pressure and weight
    • preventing diabetes when possible, or getting good medical care to treat it if necessary
    • taking prescribed medications such as cholesterol-lowering drugs.

    The bottom line

    It’s probably best to move past the idea of there being a single best diet. The overall pattern of your diet and your portion sizes are probably more important. For most people, it’s also a good idea to move away from restrictive diets that are nearly impossible to stick with and toward healthier overall eating patterns. The portfolio diet checks both those boxes.

    There’s a lot of overlap between the portfolio diet and other healthy diets. So, no one should be suggesting it’s the best diet ever. But if you’re trying to eat healthier, it’s a great place to start.

    About the Author

    photo of Robert H. Shmerling, MD

    Robert H. Shmerling, MD, Senior Faculty Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

    Dr. Robert H. Shmerling is the former clinical chief of the division of rheumatology at Beth Israel Deaconess Medical Center (BIDMC), and is a current member of the corresponding faculty in medicine at Harvard Medical School. … See Full Bio View all posts by Robert H. Shmerling, MD

  • A muscle-building obsession in boys: What to know and do

    A muscle-building obsession in boys: What to know and do

    A shadowy, heavily-muscled superhero in a red cape strikes an action pose against a red and orange background; concept is body dysmorphic disorder

    By the time boys are 8 or 10, they’re steeped in Marvel action heroes with bulging, oversized muscles and rock-hard abs. By adolescence, they’re deluged with social media streams of bulked-up male bodies.

    The underlying messages about power and worth prompt many boys to worry and wonder about how to measure up. Sometimes, negative thoughts and concerns even interfere with daily life, a mental health issue known body dysmorphic disorder, or body dysmorphia. The most common form of this in boys is muscle dysmorphia.

    What is muscle dysmorphia?

    Muscle dysmorphia is marked by preoccupation with a muscular and lean physique. While the more extreme behaviors that define this disorder appear only in a small percentage of boys and young men, it may color the mindset of many more.

    Nearly a quarter of boys and young men engage in some type of muscle-building behaviors. “About 60% of young boys in the United States mention changing their diet to become more muscular,” says Dr. Gabriela Vargas, director of the Young Men’s Health website at Boston Children’s Hospital. “While that may not meet the diagnostic criteria of muscle dysmorphia disorder, it’s impacting a lot of young men.”

    “There’s a social norm that equates muscularity with masculinity,” Dr. Vargas adds. “Even Halloween costumes for 4- and 5-year-old boys now have padding for six-pack abs. There’s constant messaging that this is what their bodies should look like.”

    Does body dysmorphic disorder differ in boys and girls?

    Long believed to be the domain of girls, body dysmorphia can take the form of eating disorders such as anorexia or bulimia. Technically, muscle dysmorphia is not an eating disorder. But it is far more pervasive in males — and insidious.

    “The common notion is that body dysmorphia just affects girls and isn’t a male issue,” Dr. Vargas says. “Because of that, these unhealthy behaviors in boys often go overlooked.”

    What are the signs of body dysmorphia in boys?

    Parents may have a tough time discerning whether their son is merely being a teen or veering into dangerous territory. Dr. Vargas advises parents to look for these red flags:

    • Marked change in physical routines, such as going from working out once a day to spending hours working out every day.
    • Following regimented workouts or meals, including limiting the foods they’re eating or concentrating heavily on high-protein options.
    • Disrupting normal activities, such as spending time with friends, to work out instead.
    • Obsessively taking photos of their muscles or abdomen to track “improvement.”
    • Weighing himself multiple times a day.
    • Dressing to highlight a more muscular physique, or wearing baggier clothes to hide their physique because they don’t think it’s good enough.

    “Nearly everyone has been on a diet,” Dr. Vargas says. “The difference with this is persistence — they don’t just try it for a week and then decide it’s not for them. These boys are doing this for weeks to months, and they’re not flexible in changing their behaviors.”

    What are the health dangers of muscle dysmorphia in boys?

    Extreme behaviors can pose physical and mental health risks.

    For example, unregulated protein powders and supplements boys turn to in hopes of quickly bulking up muscles may be adulterated with stimulants or even anabolic steroids. “With that comes an increased risk of stroke, heart palpitations, high blood pressure, and liver injury,” notes Dr. Vargas.

    Some boys also attempt to gain muscle through a “bulk and cut” regimen, with periods of rapid weight gain followed by periods of extreme calorie limitation. This can affect long-term muscle and bone development and lead to irregular heartbeat and lower testosterone levels.

    “Even in a best-case scenario, eating too much protein can lead to a lot of intestinal distress, such as diarrhea, or to kidney injury, since our kidneys are not meant to filter out excessive amounts of protein,” Dr. Vargas says.

    The psychological fallout can also be dramatic. Depression and suicidal thoughts are more common in people who are malnourished, which may occur when boys drastically cut calories or neglect entire food groups. Additionally, as they try to achieve unrealistic ideals, they may constantly feel like they’re not good enough.

    How can parents encourage a healthy body image in boys?

    These tips can help:

    • Gather for family meals. Schedules can be tricky. Yet considerable research shows physical and mental health benefits flow from sitting down together for meals, including a greater likelihood of children being an appropriate weight for their body type.
    • Don’t comment on body shape or size. “It’s a lot easier said than done, but this means your own body, your child’s, or others in the community,” says Dr. Vargas.
    • Frame nutrition and exercise as meaningful for health. When you talk with your son about what you eat or your exercise routine, don’t tie hoped-for results to body shape or size.
    • Communicate openly. “If your son says he wants to exercise more or increase his protein intake, ask why — for his overall health, or a specific body ideal?”
    • Don’t buy protein supplements. It’s harder for boys to obtain them when parents won’t allow them in the house. “One alternative is to talk with your son’s primary care doctor or a dietitian, who can be a great resource on how to get protein through regular foods,” Dr. Vargas says.

    About the Author

    photo of Maureen Salamon

    Maureen Salamon, Executive Editor, Harvard Women's Health Watch

    Maureen Salamon is executive editor of Harvard Women’s Health Watch. She began her career as a newspaper reporter and later covered health and medicine for a wide variety of websites, magazines, and hospitals. Her work has … See Full Bio View all posts by Maureen Salamon

    About the Reviewer

    photo of Howard E. LeWine, MD

    Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

    Dr. Howard LeWine is a practicing internist at Brigham and Women’s Hospital in Boston, Chief Medical Editor at Harvard Health Publishing, and editor in chief of Harvard Men’s Health Watch. See Full Bio View all posts by Howard E. LeWine, MD

  • New surgery for benign prostate hyperplasia provides long-lasting benefits

    New surgery for benign prostate hyperplasia provides long-lasting benefits

    A row of urinals in a public restroom, with light-colored dividers between them.

    Most men over 50 will develop an enlarged prostate. Also called benign prostatic hyperplasia (BPH), this bothersome condition makes it hard to urinate and can eventually lead to other problems, such as infections, kidney stones, and bladder damage, if left untreated. Many different BPH therapies are available, including medications and various types of surgery.

    One of the newer surgical options, called aquablation, trims excess prostate tissues with highly pressurized jets of saline. Doctors perform aquablation in the operating room while looking at the prostate gland on an ultrasound machine. Patients are put under general anesthesia, so they don’t feel any pain during the procedure.

    Men typically have to urinate through a catheter for about 24 hours after surgery until swelling of the urethra (the tube through which urine flows out of the bladder) subsides. Aquablation is gaining in popularity — in part because, unlike other more traditional BPH treatments, it can preserve normal ejaculation.

    In September, researchers published a study showing that improvements in urinary function from aquablation were still holding up after five years.

    Results of data analysis

    The study assessed long-term data from two clinical trials. The first, called the WATER trial (for Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue) launched in 2015 and enrolled 116 men with prostates ranging up to 80 cubic centimeters. The second trial, WATER II, launched in 2017 and enrolled 101 men with prostates ranging between 80 and 150 cubic centimeters. (Normal prostates range from 25 to 30 cubic centimeters in size.) Enrolled patients had a median age of 66 in the WATER study and 68 in WATER II. In addition, 92% of men in the WATER trial were sexually active, as were 75% of the men in WATER II.

    Both clinical trials used the so-called International Prostate Symptom Score (IPSS) to measure treatment-related improvements in urinary functioning and quality of life. Calculated based on how patients rate their symptoms on a standardized questionnaire, IPSS scores fall into three categories: mild symptom scores range from 1 to 7; intermediate symptom scores range from 8 to 18; and scores greater than 19 indicate severe symptoms.

    When they first enrolled in the trials, men in the WATER and WATER II studies reported average IPSS scores of 22.9 and 23.3 respectively. Five years later, the average respective scores were much lower: 7.0 and 6.8. The average length of hospital stay was 1.4 days in the WATER group and 1.6 days for the WATER II group. Only 1% of men were taking BPH medications after five years, and fewer than 5% had been surgically re-treated.

    Another randomized control trial, WATER III, is currently underway in Europe. That trial compares aquablation with a more established type of BPH surgery, prostate enucleation, which uses a laser to remove obstructing tissues. Six-month data reported in 2023 showed that men in either group had comparable symptom improvements.

    However, 98% of men in the prostate enucleation group had ejaculatory dysfunction. That side effect is caused by damage to delicate tissues around the bladder neck that propel semen out of the body. Semen therefore flows back into the bladder, a condition called retrograde ejaculation. None of the men in the aquablation group reported ejaculatory problems.

    A word of caution

    Aquablation can result in extended bleeding, cautions Dr. Heidi Rayala, an assistant professor of urology at Harvard Medical School and a member of the Harvard Medical School Guide to Prostate Diseases advisory board. That’s because unlike other types of surgery for BPH, including prostate enucleation, aquablation doesn’t cauterize tissues with heat. “I tell my patients to expect some blood in the urine for about four to six weeks after the procedure,” Dr. Rayala said.

    Moreover, aquablation may be unsuitable for some men who take blood thinners to prevent blood from clotting, according to Dr. Rayala. Appropriate candidates for the surgery must be able to “safely discontinue anticoagulant medications during post-operative healing, given the bleeding risk,” Dr. Rayala said. Still, aquablation is an excellent option for most men, Dr. Rayala said, especially those with medium to large prostates “who want a durable solution with a lower risk of sexual side effects.”

    “These early results are encouraging, but limited by a relatively small number of patients,” said Dr. Marc Garnick, the Gorman Brothers Professor of Medicine at Harvard Medical School and Beth Israel Deaconess Medical Center, and editor in chief of the Harvard Medical School Guide to Prostate Diseases. “Further evidence with a significantly larger number of patients and longer follow-up will help to support this new method of reducing prostate tissue as an important treatment option.”

    About the Author

    photo of Charlie Schmidt

    Charlie Schmidt, Editor, Harvard Medical School Annual Report on Prostate Diseases

    Charlie Schmidt is an award-winning freelance science writer based in Portland, Maine. In addition to writing for Harvard Health Publishing, Charlie has written for Science magazine, the Journal of the National Cancer Institute, Environmental Health Perspectives, … See Full Bio View all posts by Charlie Schmidt

    About the Reviewer

    photo of Marc B. Garnick, MD

    Marc B. Garnick, MD, Editor in Chief, Harvard Medical School Annual Report on Prostate Diseases; Editorial Advisory Board Member, Harvard Health Publishing

    Dr. Marc B. Garnick is an internationally renowned expert in medical oncology and urologic cancer. A clinical professor of medicine at Harvard Medical School, he also maintains an active clinical practice at Beth Israel Deaconess Medical … See Full Bio View all posts by Marc B. Garnick, MD

  • Think your child has ADHD? What your pediatrician can do

    Think your child has ADHD? What your pediatrician can do

    A green blackboard with the letters A D H D in chalk, with hand-drawn, squiggly arrows in multiple colors of chalk pointing outward in all directions from the letters.

    ADHD, or attention deficit hyperactivity disorder, is the most common neurobehavioral disorder of childhood. It affects approximately 7% to 8% of all children and youth in the US. As the American Academy of Pediatrics (AAP) points out in their clinical practice guideline for ADHD, that’s more than the mental health system can handle, which means that pediatricians need to step up and help out.

    So, if your child is having problems with attention, focus, hyperactivity, impulsivity, or some combination of those, and is at least 4 years old, your first step should be an appointment with your child’s primary care doctor.

    What steps will your pediatrician take?

    According to the AAP, here’s what your doctor should do:

    Take a history. Your doctor should ask you lots of questions about what is going on. Be ready to give details and examples.

    Ask you to fill out a questionnaire about your child. Your doctor should also give you a questionnaire to give to your child’s teacher or guidance counselor.

    A diagnosis of ADHD is made only if a child has symptoms that are

    • present in more than one setting: For most children, that would be both home and school. If symptoms are only present in one setting, it’s less likely to be ADHD and more likely to be related to that setting. For example, a child who only has problems at school may have a learning disability.
    • causing a problem in both of those settings: If a child is active and/or easily distracted, but is getting good grades, isn’t causing problems in class, and has good relationships in school and at home, there is not a problem. It bears watching, but it could be just personality or temperament.

    There are ADHD rating scales that have been studied and shown to be reliable, such as the Vanderbilt and the Conners assessments. These scales can be very helpful, not just in making diagnoses, but also in following the progress of a child over time.

    Screen your child for other problems. There are problems that can mimic ADHD, such as learning disabilities, depression, or even hearing problems. Additionally, children who have ADHD can also have learning disabilities, depression, or substance use. It’s important to ask enough questions and get enough information to be sure.

    Discussing treatment options for ADHD

    If a diagnosis of ADHD is made, your pediatrician should discuss treatment options with you.

    • For 4- and 5-year-olds: The best place to begin is really with parent training on managing behavior, and getting support in the classroom. Medications should only be considered in this age group if those interventions don’t help, and the child’s symptoms are causing significant problems.
    • For 6- to 12-year-olds: Along with parent training and behavioral support, medications can be very helpful. Primary care providers can prescribe one of the FDA-approved medications for ADHD (stimulants, atomoxetine, guanfacine, or clonidine). In this age group, formal classroom support in the form of an Individualized Education Program (IEP) or a 504 plan should be in place.
    • For 12- to 18-year-olds: The same school programs and behavioral health support should be in place. Medications can be helpful, but teens should be part of that decision process; shared decision-making is an important part of caring for teens, and for getting them ready to take on their own care when they become adults.

    Follow-up care for a child with ADHD

    Your pediatrician also should follow up with you and your child. Early on, there should be frequent visits while you figure out the diagnosis, as well as any other possible problems. And if medication is prescribed, frequent visits are needed initially as you figure out the best medication and dose and monitor for side effects.

    After that, the frequency of the visits will depend on how things are going, but appointments should be regular and scheduled, not just made to respond to a problem. ADHD can be a lifelong problem, bringing different challenges at different times, and it’s important that you, your child, and your doctor meet regularly so that you can best meet those challenges.

    Because together, you can.

    Watch a video of Dr. Erica Lee discussing behavioral therapies to help children with ADHD.

    About the Author

    photo of Claire McCarthy, MD

    Claire McCarthy, MD, Senior Faculty Editor, Harvard Health Publishing

    Claire McCarthy, MD, is a primary care pediatrician at Boston Children’s Hospital, and an assistant professor of pediatrics at Harvard Medical School. In addition to being a senior faculty editor for Harvard Health Publishing, Dr. McCarthy … See Full Bio View all posts by Claire McCarthy, MD

  • Are you getting health care you don’t need?

    Are you getting health care you don’t need?

    illustration in shades of green and white showing stylized medical objects: thermometer, bandage, medication bottle, stethoscope, syringe, clipboard, blister pack of pills

    Ever wonder if every medical test or treatment you've taken was truly necessary? Or are you inclined to get every bit of health care you can? Maybe you feel good about getting the most out of your health insurance. Perhaps a neighborhood imaging center is advertising discounted screening tests, your employer offers health screens as a perk, or you're intrigued by ads touting supplements for a seemingly endless number of conditions.

    But keep in mind: just because you could get a particular test or treatment or take a supplement doesn't mean you should. One study suggests that as much as 20% of all health care in the US is unneeded. In short: when it comes to health care, more is not always better.

    Isn't it better to be proactive about your health?

    We're all taught that knowledge is power. So it might seem reasonable to want to know as much as possible about how your body is working. And isn't it better to take action before there's a problem rather than waiting for one to develop? What's the harm of erring on the side of more rather than less?

    The truth is that knowledge is not always power: if the information is irrelevant to your specific situation, redundant, or inaccurate, the knowledge gained through unnecessary health care can be unhelpful or even harmful. Unnecessary tests, treatments, and supplements come with risks, even when they seem harmless. And, of course, unnecessary care is not free — even if you're not paying a cent out of pocket, it drives up costs across health systems.

    Screening tests, wellness strategies, and treatments to reconsider

    Recommended screening tests, treatments, and supplements can be essential to good health. But when risks of harm outweigh benefits — or if proof of any benefit is lacking — think twice. Save your time, money, and effort for health care that is focused on the most important health threats and backed by evidence.

    Cancer screening: When to stop?

    Screening tests for some cancers are routinely recommended and can be lifesaving. But there's a reason they come with a recommended stop age. For instance, guidelines recommend that a person at average risk of colorectal cancer with previously normal colonoscopies stop having them once they turn 75. Similar limits apply to Pap smears (age 65) and mammograms (age 75). Studies suggest that beyond those ages, there is little benefit to continuing these screens.

    Watch out for wellness marketing

    Dietary supplements are a multibillion-dollar industry. And a whopping 70% or more of US adults take at least one, such as vitamin D, fish oil, or a multivitamin. People often consider them as insurance in case vital elements are missing from their diet, or they believe supplements can prevent dementia, heart disease, or another condition.

    Yet little evidence supports a benefit of routine supplement use for everyone. While recent studies suggest a daily multivitamin might slow cognitive decline in older adults, there's no medical consensus that everyone should be taking a multivitamin. Fish oil (omega-3) supplements haven't proven to be as healthful as simply eating servings of fatty fish and other seafood low in toxic chemicals like mercury and PCBs. And the benefits of routinely taking vitamin D supplements remain unproven as well.

    It's worth emphasizing that dietary supplements clearly provide significant benefit for some people, and may be recommended by your doctor accordingly. For example, if you have a vitamin or mineral deficiency or a condition like age-related macular degeneration, good evidence supports taking specific supplements.

    Reconsider daily aspirin

    Who should be taking low-dose aspirin regularly? Recommendations have changed in recent years, so this is worth revisiting with your health care team.

    • Older recommendations favored daily low-dose aspirin to help prevent cardiovascular disease, including first instances of heart attack and stroke.
    • New recommendations favor low-dose aspirin for people who've already experienced a heart attack, stroke, or other cardiovascular disease. Adults ages 40 to 59 who are at a high risk for these conditions and low risk for bleeding also may consider it.

    Yet according to a recent study, nearly one-third of adults 60 and older without past cardiovascular disease take aspirin, despite evidence that it provides little benefit for those at average or low risk. Aspirin can cause stomach bleeding and raise risk for a certain type of stroke.

    Weigh in on prostate cancer screening

    Men hear about prostate cancer often. It's common, and the second leading cause of cancer deaths among men. But PSA blood tests and rectal exams to identify evidence of cancer in the prostate are no longer routinely recommended for men ages 55 to 69 by the United States Preventative Services Task Force.

    The reason? Studies suggest that performing these tests does not reliably reduce suffering or prolong life. Nor do possible benefits offset downsides like false positives (test results that are abnormal despite the absence of cancer). That can lead to additional testing, some of which is invasive.

    Current guidelines suggest making a shared decision with your doctor about whether to have PSA testing after reviewing the pros and cons. For men over age 70, no screening is recommended. Despite this, millions of men have PSA tests and rectal examinations routinely.

    Not everyone needs heart tests

    There are now more ways than ever to evaluate the health of your heart. But none are routinely recommended if you're at low risk and have no signs or symptoms of cardiovascular disease. That's right: in the absence of symptoms or a high risk of cardiovascular disease, it's generally safe to skip EKGs, stress tests, and other cardiac tests.

    Yet many people have these tests as part of their routine care. Why is this a problem? Having these tests without a compelling reason comes with risks, especially false positive results that can lead to invasive testing and unneeded treatment.

    Four more reasons to avoid unnecessary care

    Besides the concerns mentioned already, there are other reasons to avoid unnecessary care, including:

    • The discomfort or complications of testing. If you're needle-phobic, getting a blood test is a big deal. And while complications of noninvasive testing are rare (such as a skin infection from a blood test), they can occur.
    • The anxiety associated with waiting to find out test results
    • False reassurance that comes with false negatives (results that are normal or nearly so, suggesting no disease when disease is actually present)
    • All treatments have side effects. Even minor reactions — like occasional nausea or constipation — seem unacceptable if there's no reason to expect benefit from treatment.

    The bottom line

    You may believe your doctor wants you to continue with your current schedule of tests and treatments, while they might think this is your preference! It's worth discussing if you haven't already, especially if you suspect you may be taking pills or getting tests you don't truly need.

    If your doctor says you can safely skip certain tests, treatments, and supplements, it doesn't mean that he or she is neglecting your health or that you don't deserve great health care! It's likely that the balance of risks and benefits simply doesn't support doing these things.

    Less unnecessary care could free up resources for those who need it most. And it could save you time, money, and unnecessary risks or side effects, thus improving your health. It's a good example of how less can truly be more.

    About the Author

    photo of Robert H. Shmerling, MD

    Robert H. Shmerling, MD, Senior Faculty Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

    Dr. Robert H. Shmerling is the former clinical chief of the division of rheumatology at Beth Israel Deaconess Medical Center (BIDMC), and is a current member of the corresponding faculty in medicine at Harvard Medical School. … See Full Bio View all posts by Robert H. Shmerling, MD

  • Should you be sleepmaxxing to boost health and happiness?

    Should you be sleepmaxxing to boost health and happiness?

    Illustration of woman with white hair and dress lying among color flowers; concept is sleepmaxxing

    If you’ve been on TikTok lately, you know it’s hard to avoid countless influencers touting a concept called sleepmaxxing. Their posts provide tips and tricks to get longer, better, and more restorative sleep. And why not? Sleep is considered a pillar of good health and is related to everything from brain health to cardiovascular health, and even diabetes.

    But what exactly is sleepmaxxing? And how likely is it to deliver on claims of amped-up energy, a boost to the immune system, reducing stress levels, and improving your mood?

    What is sleepmaxxing?

    Depending on which social media platform you happen to be looking at, the recommended strategies for maximizing sleep differ. Tips include:

    • taping your mouth shut while sleeping
    • not drinking anything during the two hours before bedtime
    • a cold room temperature
    • a dark bedroom
    • using a white noise machine
    • not setting a morning alarm
    • showering one hour before bedtime
    • eliminating caffeine
    • eating kiwis before going to bed
    • taking magnesium and melatonin
    • using weighted blankets
    • getting 30 minutes of sunlight every day
    • meditating daily for 30 minutes.

    Does any research support sleepmaxxing?

    A thorough search through PubMed, PsycNet, and Google Scholar reveals zero results for the terms “sleepmaxx” and “sleepmaxxing.” But wait — this certainly doesn’t mean that some influencer-recommended strategies are not evidence-based, just that the concept of sleepmaxxing, as a defined package, has not been scientifically studied. But yes, some of the strategies — including one uncomfortable, though popular, choice — lack evidence.

    Can mouth-taping improve your sleep?

    TikTok users have claimed that taping your mouth while you sleep has benefits, such as reducing snoring and improving bad breath. A team from the department of otolaryngology at George Washington University was prompted by all of the social media buzz on the topic to review research on the impact of nocturnal mouth taping. Spoiler alert: the authors note that most TikTok mouth-taping claims aren’t supported by research.

    If you do snore, it’s important to discuss this with your medical team. Even if taping your mouth reduces your snoring, it can’t effectively treat a potential underlying cause of the snoring, such as allergies, asthma, or sleep apnea.

    Sleepmaxxing or basic sleep hygiene?

    Many strategies recommended by sleepmaxxers are essentially what sleep experts prescribe as good sleep hygiene, which has plenty of research backing its value. Common components of sleep hygiene are decreasing caffeine and alcohol consumption, increasing physical activity, sleep timing, reducing evening light exposure, limiting daytime naps, and having a cool bedroom.

    While tips like these help many people enjoy restful sleep, those who have an insomnia disorder will need more help, as described below.

    Melatonin, early bedtime, weighted blankets, and — kiwi fruit?

    Other strategies suggested by sleepmaxxers are based on limited scientific data. For example:

    • Taking melatonin is recommended by the American Academy of Sleep Medicine to treat circadian rhythm disorders such as jet lag. But it’s not recommended for insufficient sleep, poor sleep quality, or difficulty with falling asleep or staying asleep.
    • Is it healthier to be asleep by 10 p.m.? One video that garnered more than a million views claims it is. While it is important to maximize morning sunlight exposure and minimize evening light exposure to regulate circadian rhythms, there is such variability in how much sleep someone requires and individual chronotypes (not to mention varying personal and professional responsibilities!) that it is difficult to state there is an ideal bedtime for everyone.
    • While intriguing research has been done on weighted blankets, there is no convincing evidence that they are truly effective for the general adult population.
    • Overall, it’s important to be cautious about the impact of the placebo effect on how someone sleeps. An analysis of more than 30 studies showed that roughly 64% of the drug response for a sleep medication in insomnia patients could be due to the placebo effect. A key takeaway is that studies that are not randomized controlled trials — such as this small study on 24 people suggesting that kiwi fruit may improve sleep — should be interpreted with a grain of salt.

    Could you have orthosomnia?

    The expectation of flawless sleep, night in and night out, is an unrealistic goal. Orthosomnia is a term that describes an unhealthy pursuit of perfect sleep. The pressure to get perfect sleep is embedded in the sleepmaxxing culture.

    With more and more people able to access daily data about their sleep and other health metrics through consumer wearables, even a person who is objectively sleeping well can become unnecessarily concerned with optimizing their sleep. While prioritizing restful sleep is commendable, setting perfection as your goal is problematic. Even good sleepers vary from night to night, experiencing less than desirable sleep a couple of times per week.

    It is also noteworthy that some of the most widely viewed recommendations on TikTok are not supported by scientific evidence.

    Do you really need to fix your sleep?

    A good first step is to understand whether or not there is anything that you need to fix! Consider tracking your sleep for a few weeks using a sleep diary, and pair this data with a consumer wearable (such as a Fitbit or Apple Watch). Both imperfectly capture sleep data when compared to the gold-standard tool sleep experts use (polysomnography, or a sleep study). However, combining the information can give you a reasonable assessment of your sleep status.

    Regularly getting restful sleep can indeed boost health and mood. And all of us can benefit from following basic sleep hygiene tips. But if it takes you 30 minutes or more to fall asleep, or if you are up for 30 minutes or more in the middle of the night, and this happens three or more times per week, then consider reaching out to your health care team to seek further evaluation.

    There are effective, nonmedication treatments that are proven to help you sleep better. One example is cognitive behavioral therapy for insomnia, which can dramatically improve insomnia symptoms in a matter of weeks.

    Want to learn more about cognitive behavioral therapy for insomnia? Watch this video from the Division of Sleep Medicine at Harvard Medical School with Eric Zhou describing how it works.

    About the Author

    photo of Eric Zhou, PhD

    Eric Zhou, PhD, Contributor

    Eric Zhou, PhD, is an assistant professor of psychiatry at Harvard Medical School. He has been invited to speak internationally about sleep health in both pediatric and adult populations, including those with chronic illnesses. His research … See Full Bio View all posts by Eric Zhou, PhD

  • Stepping up activity if winter slowed you down

    Stepping up activity if winter slowed you down

    A close up of man's hand pointing a TV remote and sock-clad feet and legs in denim jeans up on a couch with TV in background showing beautiful blue skies, trees, and puffy clouds outside

    If you've been cocooning due to winter’s cold, who can blame you? But a lack of activity isn't good for body or mind during any season. And whether you're deep in the grip of winter or fortunate to be basking in signs of spring, today is a good day to start exercising. If you’re not sure where to start — or why you should — we’ve shared tips and answers below.

    Moving more: What’s in it for all of us?

    We’re all supposed to strengthen our muscles at least twice a week and get a total at least 150 minutes of weekly aerobic activity (the kind that gets your heart and lungs working). But fewer than 18% of U.S. adults meet those weekly recommendations, according to the CDC.

    How can choosing to become more active help? A brighter mood is one benefit: physical activity helps ease depression and anxiety, for example. And being sufficiently active — whether in short or longer chunks of time — also lowers your risk for health problems like

    • heart disease
    • stroke
    • diabetes
    • cancer
    • brain shrinkage
    • muscle loss
    • weight gain
    • poor posture
    • poor balance
    • back pain
    • and even premature death.

    What are your exercise obstacles?

    Even when we understand these benefits, a range of obstacles may keep us on the couch.

    Don’t like the cold? Have trouble standing, walking, or moving around easily? Just don’t like exercise? Don’t let obstacles like these stop you anymore. Try some workarounds.

    • If it’s cold outside: It’s generally safe to exercise when the mercury is above 32° F and the ground is dry. The right gear for cold doesn’t need to be fancy. A warm jacket, a hat, gloves, heavy socks, and nonslip shoes are a great start. Layers of athletic clothing that wick away moisture while keeping you warm can help, too. Consider going for a brisk walk or hike, taking part in an orienteering event, or working out with battle ropes ($25 and up) that you attach to a tree.
    • If you have mobility issues: Most workouts can be modified. For example, it might be easier to do an aerobics or weights workout in a pool, where buoyancy makes it easier to move and there’s little fear of falling. Or try a seated workout at home, such as chair yoga, tai chi, Pilates, or strength training. You’ll find an endless array of free seated workout videos on YouTube, but look for those created by a reliable source such as Silver Sneakers, or a physical therapist, certified personal trainer, or certified exercise instructor. Another option is an adaptive sports program in your community, such as adaptive basketball.
    • If you can’t stand formal exercise: Skip a structured workout and just be more active throughout the day. Do some vigorous housework (like scrubbing a bathtub or vacuuming) or yard work, climb stairs, jog to the mailbox, jog from the parking lot to the grocery store, or do any activity that gets your heart and lungs working. Track your activity minutes with a smartphone (most devices come with built-in fitness apps) or wearable fitness tracker ($20 and up).
    • If you’re stuck indoors: The pandemic showed us there are lots of indoor exercise options. If you’re looking for free options, do a body-weight workout, with exercises like planks and squats; follow a free exercise video online; practice yoga or tai chi; turn on music and dance; stretch; or do a resistance band workout. Or if it’s in the budget, get a treadmill, take an online exercise class, or work online with a personal trainer. The American Council on Exercise has a tool on its website to locate certified trainers in your area.

    Is it hard to find time to exercise?

    The good news is that any amount of physical activity is great for health. For example, a 2022 study found that racking up 15 to 20 minutes of weekly vigorous exercise (less than three minutes per day) was tied to lower risks of heart disease, cancer, and early death.

    "We don't quite understand how it works, but we do know the body's metabolic machinery that imparts health benefits can be turned on by short bouts of movement spread across days or weeks," says Dr. Aaron Baggish, founder of Harvard-affiliated Massachusetts General Hospital's Cardiovascular Performance Program and an associate professor of medicine at Harvard Medical School.

    And the more you exercise, Dr. Baggish says, the more benefits you accrue, such as better mood, better balance, and reduced risks of diabetes, high blood pressure, high cholesterol, and cognitive decline.

    What’s the next step to take?

    For most people, increasing activity is doable. If you have a heart condition, poor balance, muscle weakness, or you’re easily winded, talk to your doctor or get an evaluation from a physical therapist.

    And no matter which activity you select, ease into it. When you’ve been inactive for a while, your muscles are vulnerable to injury if you do too much too soon.

    “Your muscles may be sore initially if they are being asked to do more,” says Dr. Sarah Eby, a sports medicine specialist at Harvard-affiliated Spaulding Rehabilitation Hospital. “That’s normal. Just be sure to start low, and slowly increase your duration and intensity over time. Pick activities you enjoy and set small, measurable, and attainable goals, even if it’s as simple as walking five minutes every day this week.”

    Remember: the aim is simply exercising more than you have been. And the more you move, the better.

    About the Author

    photo of Heidi Godman

    Heidi Godman, Executive Editor, Harvard Health Letter

    Heidi Godman is the executive editor of the Harvard Health Letter. Before coming to the Health Letter, she was an award-winning television news anchor and medical reporter for 25 years. Heidi was named a journalism fellow … See Full Bio View all posts by Heidi Godman

    About the Reviewer

    photo of Howard E. LeWine, MD

    Howard E. LeWine, MD, Chief Medical Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

    Dr. Howard LeWine is a practicing internist at Brigham and Women’s Hospital in Boston, Chief Medical Editor at Harvard Health Publishing, and editor in chief of Harvard Men’s Health Watch. See Full Bio View all posts by Howard E. LeWine, MD

  • Supporting a loved one with prostate cancer: A guide for caregivers

    Supporting a loved one with prostate cancer: A guide for caregivers

    A middle-age couple having a serious conversation while sitting on the couch in their home; the husband has his hands clasped together and the wife looks sympathetic as she listens to him.

    Looking after a loved one who has prostate cancer can be overwhelming. Caregivers — usually partners, family members, or close friends — play crucial roles in supporting a patient's physical and psychological well-being. But what does that entail? You as a caregiver might not know what to say or how to help.

    "Patients diagnosed with advanced cancer are facing their own mortality," says Dr. Marc Garnick, the Gorman Brothers Professor of Medicine at Harvard Medical School and Beth Israel Deaconess Medical Center, and editor in chief of the Harvard Medical School Guide to Prostate Diseases. "And they each process that in different ways."

    Dr. Garnick emphasizes the need provide patients and families with the best information possible about the specifics of the diagnosis, symptoms, and available treatments. Some patients have near-miraculous responses to treatment, he says, even when they have very advanced cancer. "We let patients know that there are reasons to be optimistic, as treatments are improving on a regular basis," he says.

    Communication

    Dr. Garnick points out that clinicians should avoid words or phrases that can leave cancer patients feeling unempowered. A phrase like "Let's not worry about that now," for instance, is dismissive and doesn't respond to a patient's legitimate concerns. Saying "You're lucky your cancer is only stage 2" doesn't allow for the fear and anxiety a patient may have over his disease.

    Along similar lines, "It's important for caregivers to be receptive to what their loved ones are saying," Dr. Garnick says. "Instead of minimizing or questioning what your loved one is telling you, try asking 'What do you need? Tell me what you think is going to help you feel better.'"

    While it's natural to offer reassurance, you should also give your loved one space to express himself openly without offering quick solutions. Be aware that treatment can lead to emotional ups and downs, so expect mood fluctuations.

    One of the most valuable tools you have as a caregiver is the relationship you've built with your loved one over the years. During this challenging time, remind yourself of the bonds you've created together. Shared memories, inside jokes, and mutual interests can provide strength and comfort.

    Day-to-day practical support

    Managing medications can be challenging. Cancer patients can take a dozen or more pills per day on varying schedules. You can help your loved one stay on track by setting up a pill organizer (available at most drugstores) that sorts medications according to when they're needed.

    Patients with advanced prostate cancer are now being treated more often with drug combinations that include chemotherapy as well as hormonal therapies. Chemotherapy can leave patients feeling unusually cold, and patients may also get cold after experiencing hot flashes from hormonal therapy. So keep lots of blankets and warm hats on hand.

    Collaborate on a journal where you and your loved one keep health information in one place. It should contain the names and contacts of clinicians on his team, as well as details of his treatment plan. The journal can also double as a diary where you both record treatment experiences.

    You might be tasked with coordinating medical appointments. It's important to keep lists of questions you may have. Take notes so you have a record of what doctors and other people on his care team have told you. Also, you should take some time to familiarize yourself with your loved one's insurance policies or Medicare plans so you have a better understanding of what's covered.

    Don't forget to take care of yourself!

    As a caregiver, it's easy to get lost in your loved one's needs. But caring for someone with cancer while managing household responsibilities can also leave you feeling isolated, burned out, and even depressed. It's essential to also prioritize your own health and well-being.

    Make sure that you get enough sleep and exercise. Keep up with your own checkups and screening. Try to eat well, and prepare meals ahead of time to reduce stress and save time on busy days. Take breaks! Caregiving can be intense, so take time to recharge by taking a walk, reading a book, or spending time with friends.

    Here are some valuable resources that can help.

    Help for Cancer Caregivers provides support on managing feelings and emotions, keeping healthy, day-to-day needs, working together, and long-distance caregiving.

    The Prostate Cancer Foundation provides an array of educational materials, including a "caregiver's toolkit" that helps caregivers understand treatment options, side effects, and ways to be actively involved in the decision-making process.

    The Patient Advocate Foundation offers case management services to help caregivers and patients understand insurance coverage, financial assistance programs, and other resources that can reduce the financial burden of cancer treatment.

    About the Author

    photo of Charlie Schmidt

    Charlie Schmidt, Editor, Harvard Medical School Annual Report on Prostate Diseases

    Charlie Schmidt is an award-winning freelance science writer based in Portland, Maine. In addition to writing for Harvard Health Publishing, Charlie has written for Science magazine, the Journal of the National Cancer Institute, Environmental Health Perspectives, … See Full Bio View all posts by Charlie Schmidt

    About the Reviewer

    photo of Marc B. Garnick, MD

    Marc B. Garnick, MD, Editor in Chief, Harvard Medical School Annual Report on Prostate Diseases; Editorial Advisory Board Member, Harvard Health Publishing

    Dr. Marc B. Garnick is an internationally renowned expert in medical oncology and urologic cancer. A clinical professor of medicine at Harvard Medical School, he also maintains an active clinical practice at Beth Israel Deaconess Medical … See Full Bio View all posts by Marc B. Garnick, MD

  • Flowers, chocolates, organ donation — are you in?

    Flowers, chocolates, organ donation — are you in?

    photo illustration of a heart shape in dark red with the words organ donors save lives on it in white

    Chocolates and flowers are great gifts for Valentine’s Day. But what if the gifts we give then or throughout the year could be truly life-changing? A gift that could save a life or free someone from dialysis?

    You can do this. For people in need of an organ, tissue, or blood donation, a donor can give them a gift that exceeds the value of anything that you can buy. Fittingly, Valentine’s Day is also known as National Donor Day, a time for blood drives and sign-ups for organ and tissue donation. Have you ever wondered what can be donated? Had reservations about donating after death or concerns about risks for live donors? Read on.

    The enormous impact of organ, tissue, or cell donation

    Imagine you have kidney failure requiring dialysis 12 or more hours each week just to stay alive. Even with this, you know you’re still likely to die a premature death. Or, if your liver is failing, you may experience severe nausea, itching, and confusion; death may only be a matter of weeks or months away. For those with cancer in need of a bone marrow transplant, or someone who’s lost their vision due to corneal disease, finding a donor may be their only good option.

    Organ or tissue donation can turn these problems around, giving recipients a chance at a long life, a better quality of life, or both. And yet, the number of people who need organ donation far exceeds compatible donors. While national surveys have found about 90% of Americans support organ donation, only 40% have signed up. More than 103,000 women, men, and children are awaiting an organ transplant in the US. About 6,200 die each year, still waiting.

    What can you donate?

    The list of ways to help has grown dramatically. Some organs, tissues, or cells can be donated while you’re alive; other donations are only possible after death. A single donor can help more than 80 people!

    After death, people can donate:

    • bone, cartilage, and tendons
    • corneas
    • face and hands (though uncommon, they are among the newest additions to this list)
    • kidneys
    • liver
    • lungs
    • heart and heart valves
    • stomach and intestine
    • nerves
    • pancreas
    • skin
    • arteries and veins.

    Live donations may include:

    • birth tissue, such as the placenta, umbilical cord, and amniotic fluid, which can be used to help heal skin wounds or ulcers and prevent infection
    • blood cells, serum, or bone marrow
    • a kidney
    • part of a lung
    • part of the intestine, liver, or pancreas.

    To learn more about different types of organ donations, visit Donate Life America.

    Becoming a donor after death: Questions and misconceptions

    Common misconceptions about becoming an organ donor limit the number of people who are willing to sign up. For example, many people mistakenly believe that

    • doctors won’t work as hard to save your life if you’re known to be an organ donor — or worse, doctors will harvest organs before death
    • their religion forbids organ donation
    • you cannot have an open-casket funeral if you donate your organs.

    None of these is true, and none should discourage you from becoming an organ donor. Legitimate medical professionals always keep the patient’s interests front and center. Care would never be jeopardized due to a person’s choices around organ donation. Most major religions allow and support organ donation. If organ donation occurs after death, the clothed body will show no outward signs of organ donation, so an open-casket funeral is an option for organ donors.

    Live donors: Blood, bone marrow, and organs

    Have you ever donated blood? Congratulations, you’re a live donor! The risk for live donors varies depending on the intended donation, such as:

    • Blood, platelets, or plasma: If you’re donating blood or blood products, there is little or no risk involved.
    • Bone marrow: Donating bone marrow requires a minor surgical procedure. If general anesthesia is used, there is a chance of a reaction to the anesthesia. Bone marrow is removed through needles inserted into the back of the pelvis bones on each side. Back or hip pain is common, but can be controlled with pain relievers. The body quickly replaces the bone marrow removed, so no long-term problems are expected.
    • Stem cells: Stem cells are found in bone marrow or umbilical cord blood. They also appear in small numbers in our blood and can be donated through a process similar to blood donation. This takes about seven or eight hours. Filgrastim, a medication that increases stem cell production, is given for a number of days beforehand. It can cause side effects such as flulike symptoms, bone pain, and fatigue, but these tend to resolve soon after the procedure.
    • Kidney, lung, or liver: Surgery to donate a kidney or a portion of a lung or liver comes with a risk of complications, reactions to anesthesia, and significant recovery time. It’s no small matter to give a kidney, or part of a lung or liver.

    The vast number of live organ donations occur without complications, and donors typically feel quite positive about the experience.

    Who can donate?

    Almost anyone can donate blood cells –– including stem cells –– or be a bone marrow, tissue, or organ donor. Exceptions include anyone with active cancer, widespread infection, or organs that aren’t healthy.

    What about age? By itself, your age does not disqualify you from organ donation. In 2023, two out of five people donating organs were over 50. People in their 90s have donated organs upon their deaths and saved the lives of others.

    However, bone marrow transplants may fail more often when the donor is older, so bone marrow donations by people over age 55 or 60 are usually avoided.

    Finding a good match: Immune compatibility

    For many transplants, the best results occur when there is immune compatibility between the donor and recipient. Compatibility is based largely on HLA typing, which analyzes genetically-determined proteins on the surface of most cells. These proteins help the immune system identify which cells qualify as foreign or self. Foreign cells trigger an immune attack; cells identified as self should not.

    HLA typing can be done by a blood test or cheek swab. Close relatives tend to have the best HLA matches, but complete strangers may be a good match as well.

    Fewer donors among people with certain HLA types make finding a match more challenging. Already existing health disparities, such as higher rates of kidney disease among Black Americans and communities of color, are worsened by lower numbers of donors from these communities, an inequity partly driven by a lack of trust in the medical system.

    The bottom line

    You can make an enormous impact by becoming a donor during your life or after death. In the US, you must opt in to be a donor after death. (Research suggests the opt-out approach many other countries use could significantly increase rates of organ donation in this country.)

    I’m hopeful that organ donation in the US and throughout the world will increase over time. While you can still go with chocolates for Valentine’s Day, maybe this year you can also go bigger and become a donor.

    About the Author

    photo of Robert H. Shmerling, MD

    Robert H. Shmerling, MD, Senior Faculty Editor, Harvard Health Publishing; Editorial Advisory Board Member, Harvard Health Publishing

    Dr. Robert H. Shmerling is the former clinical chief of the division of rheumatology at Beth Israel Deaconess Medical Center (BIDMC), and is a current member of the corresponding faculty in medicine at Harvard Medical School. … See Full Bio View all posts by Robert H. Shmerling, MD